ITN1358
ITN1358
- Catalog: ITN1358
- Gene/Protein: SPAG5
- Product Description: Immunotag™ SPAG5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SPAG5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SPAG5 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SPAG5 |
| Accession No. | Q96R06 Q7TME2 |
| Description | sperm associated antigen 5(SPAG5) Homo sapiens This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. [provided by RefSeq, Jul 2008], |
| Protein Expression | Cervix carcinoma,Epithelium,Lung,Testis, |
| Subcellular Localization | kinetochore,condensed chromosome kinetochore,spindle pole,nucleus,nucleoplasm,cytoplasm,spindle microtubule,midbody,centriolar satellite,microtubule plus-end,mitotic spindle, |
| Protein Function | function:Necessary for normal spindle formation during mitosis.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:In a punctate pattern in interphase cells. During mitosis, detected at spindle poles during prophase, throughout the spindle in metaphase and anaphase, and at midzone microtubules in anaphase and telophase. Detected on kinetochores of chromosomes that have congressed.,subunit:Homodimer, with a globular head domain and a long stalk. Homo-oligomer; the globular head domains associate, resulting in aster-like structures. Binds to microtubules in the mitotic spindle.,tissue specificity:Highly expressed in testis. Detected at low levels in placenta, liver, pancreas, thymus and colon., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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