ITN1370
ITN1370
- Catalog: ITN1370
- Gene/Protein: SOAT1 ACACT ACACT1 ACAT ACAT1 SOAT STAT
- Product Description: Immunotag™ SOAT1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SOAT1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SOAT1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SOAT1 ACACT ACACT1 ACAT ACAT1 SOAT STAT |
| Accession No. | P35610 Q61263 O70536 |
| Description | sterol O-acyltransferase 1(SOAT1) Homo sapiens The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011], |
| Cell Pathway/ Category | Steroid biosynthesis, |
| Protein Expression | Macrophage,Placenta, |
| Subcellular Localization | endoplasmic reticulum,endoplasmic reticulum membrane,membrane,integral component of membrane, |
| Protein Function | catalytic activity:Acyl-CoA + cholesterol = CoA + cholesterol ester.,disease:Accumulation of insoluble cholesterol esters in macrophages and smooth muscle is a characteristic feature of early lesions of atherosclerotic plaque.,function:Catalyzes the formation of fatty acid-cholesterol esters. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase.,induction:Highly activated by the presence of cholesterol.,similarity:Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.,subunit:May form homo- or heterodimers., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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