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ITN1379

ITN1379
  • Catalog: ITN1379
  • Gene/Protein: UBASH3B KIAA1959 STS1
  • Product Description: Immunotag™ UBS3B Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ UBS3B Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein UBS3B
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity UBS3B Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name UBASH3B KIAA1959 STS1
Accession No. Q8TF42 Q8BGG7
Description ubiquitin associated and SH3 domain containing B(UBASH3B) Homo sapiens This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. [provided by RefSeq, Jul 2008],
Protein Expression Brain,Kidney,Liver,Placenta,Platelet,
Subcellular Localization nucleus,cytoplasm,
Protein Function function:Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface.,similarity:Contains 1 SH3 domain.,similarity:Contains 1 UBA domain.,subunit:Interacts with CBL. Part of a complex containing CBL and activated EGFR. Interacts with ubiquitin and with mono-ubiquitinated proteins.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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