ITN1400
ITN1400
- Catalog: ITN1400
- Gene/Protein: TLX1 HOX11 TCL3
- Product Description: Immunotag™ TLX1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TLX1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TLX1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | TLX1 HOX11 TCL3 |
| Accession No. | P31314 P43345 |
| Description | T-cell leukemia homeobox 1(TLX1) Homo sapiens This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010], |
| Protein Expression | Pooled, |
| Subcellular Localization | nucleus, |
| Protein Function | disease:A chromosomal aberration involving TLX1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(10;14)(q24;q11) with TCRD.,function:Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.,miscellaneous:TLX1 is oriented in a head-to-head manner with TDI. Both genes share the same promoter with robust bidirectional activity.,similarity:Contains 1 homeobox DNA-binding domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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