ITN1426
ITN1426
- Catalog: ITN1426
- Gene/Protein: TCF20 KIAA0292 SPBP
- Product Description: Immunotag™ TCF20 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TCF20 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TCF20 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | TCF20 KIAA0292 SPBP |
| Accession No. | Q9UGU0 Q9EPQ8 |
| Description | transcription factor 20(TCF20) Homo sapiens This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015], |
| Protein Expression | Brain,Epithelium, |
| Subcellular Localization | nucleus,nucleoplasm, |
| Protein Function | domain:The atypical PHD domain functions as a negative modulator of cofactor binding.,function:Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 A.T hook DNA-binding domain.,similarity:Contains 1 PHD-type zinc finger.,subunit:Homodimer (Probable). Interacts with RNF4 and JUN.,tissue specificity:Expressed in most tissues, except in ovary and prostate. Isoform 1 is exclusively expressed in brain, heart and testis, and this form predominates in liver and kidney. Isoform 2 predominates in lung., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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