ITN1448
ITN1448
- Catalog: ITN1448
- Gene/Protein: SEC62 TLOC1
- Product Description: Immunotag™ SEC62 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | SEC62 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | SEC62 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | SEC62 TLOC1 |
Accession No. | Q99442 Q8BU14 |
Description | SEC62 homolog, preprotein translocation factor(SEC62) Homo sapiens The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008], |
Protein Expression | Epithelium,Liver,Mammary gland,Prostate, |
Subcellular Localization | endoplasmic reticulum,endoplasmic reticulum membrane,rough endoplasmic reticulum,cytosol,membrane,integral component of membrane,aggresome,intermediate filament cytoskeleton, |
Protein Function | function:Required for preprotein translocation.,similarity:Belongs to the SEC62 family.,subunit:Part of a complex that contains SEC61, SEC62 and SEC63. Interacts with SEC61B., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |