Datasheet |
|
Target Protein |
VATG2 |
Clonality |
Polyclonal |
Storage/Stability |
-20°C/1 year |
Application |
WB,ELISA |
Recommended Dilution |
WB 1:500-2000 ELISA 1:5000-20000 |
Concentration |
1 mg/ml |
Reactive Species |
Human,Mouse |
Host Species |
Rabbit |
Immunogen |
Synthesized peptide derived from part region of human protein |
Specificity |
VATG2 Polyclonal Antibody detects endogenous levels of protein. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form |
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name |
ATP6V1G2 ATP6G ATP6G2 NG38 |
Accession No. |
O95670 Q9WTT4 |
Description |
ATPase H+ transporting V1 subunit G2(ATP6V1G2) Homo sapiens This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene |
Cell Pathway/ Category |
Oxidative phosphorylation,Vibrio cholerae infection,Epithelial cell signaling in Helicobacter pylori infection, |
Protein Expression |
Brain,PCR rescued clones,Peripheral blood leukocyte,Peripheral Nerv |
Subcellular Localization |
cytosol,vacuolar proton-transporting V-type ATPase complex,integral component of synaptic vesicle membrane,melanosome, |
Protein Function |
function:Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.,similarity:Belongs to the V-ATPase G subunit family.,subcellular location:Highly enriched in late-stage melanosomes.,subunit:V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).,tissue specificity:Brain., |
Usage |
For Research Use Only! Not for diagnostic or therapeutic procedures. |