ITN1616
ITN1616
- Catalog: ITN1616
- Gene/Protein: LAMTOR3 MAP2K1IP1 MAPKSP1 PRO2783
- Product Description: Immunotag™ LTOR3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | LTOR3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 30-110 |
| Specificity | LTOR3 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | LAMTOR3 MAP2K1IP1 MAPKSP1 PRO2783 |
| Accession No. | Q9UHA4 O88653 Q5U204 |
| Description | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3(LAMTOR3) Homo sapiens This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein, |
| Protein Expression | Brain,Dendritic cell,Fetal liver,Liver,Lung |
| Subcellular Localization | lysosomal membrane,focal adhesion,endosome membrane,extracellular exosome,Ragulator complex, |
| Protein Function | function:Adapter protein that enhances the efficiency of the MAP kinase cascade. Facilitates the activation of MAPK2.,similarity:Belongs to the MAPKSP1 family.,subunit:Interacts with MAP2K1 and MAPK2. Interacts with MORG1 (By similarity). Heterodimer with MAPBPIP., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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