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ITN1630

ITN1630
  • Gene/Protein: TAF1B
  • Product Description: Immunotag™ TAF1B Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ TAF1B Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein TAF1B
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity TAF1B Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name TAF1B
Accession No. Q53T94 P97358 D3ZYB7
Description TATA-box binding protein associated factor, RNA polymerase I subunit B(TAF1B) Homo sapiens Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016],
Protein Expression Colon,Corpus callosum,
Subcellular Localization nucleus,nucleoplasm,RNA polymerase transcription factor SL1 complex,extracellular exosome,RNA polymerase I core factor complex,
Protein Function function:Component of the transcription factor SL1/TIFIB complex involved in the assembly of the PIC (preinitiation complex).,similarity:Belongs to the TAF1 family.,subunit:Component of the transcription factor SL1/TIFIB complex which is composed of TBP and at least TAF1A, TAF1B and TAF1C. In the complex, interacts directly with TBP, TAF1A and TAF1C. Interaction of the SL1/TIFIB subunits with TBP excludes interaction with the transcription factor IID (TFIID) subunits. This mutually exclusive binding directs the formation of promoter and RNA polymerase-selective TBP-TAF complexes.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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