ITN1634
ITN1634
- Catalog: ITN1634
- Gene/Protein: SNAPC4 SNAP190
- Product Description: Immunotag™ SNPC4 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | SNPC4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | SNPC4 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | SNAPC4 SNAP190 |
Accession No. | Q5SXM2 Q8BP86 |
Description | small nuclear RNA activating complex polypeptide 4(SNAPC4) Homo sapiens This gene encodes the largest subunit of the small nuclear RNA-activating protein (SNAP) complex. The encoded protein contains a Myb DNA-binding domain, and is essential for RNA polymerase II and III polymerase transcription from small nuclear RNA promoters. A mutation in this gene is associated with ankylosing spondylitis. [provided by RefSeq, Jul 2016], |
Protein Expression | Epithelium,Teratocarcinoma, |
Subcellular Localization | nucleus,nucleoplasm,snRNA-activating protein complex, |
Protein Function | function:Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.,similarity:Contains 2 Myb-like domains.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC4 interacts with SNAPC1, SNAPC2, SNAPC5, BRF2 and TBP., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |