ITN1745
ITN1745
- Catalog: ITN1745
- Gene/Protein: GRIK5 GRIK2
- Product Description: Immunotag™ GRIK5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GRIK5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 910-990 |
| Specificity | GRIK5 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | GRIK5 GRIK2 |
| Accession No. | Q16478 Q61626 Q63273 |
| Description | glutamate ionotropic receptor kainate type subunit 5(GRIK5) Homo sapiens This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Erythroleukemia,Hippocampus, |
| Subcellular Localization | endoplasmic reticulum,plasma membrane,postsynaptic density,cell junction,dendrite,kainate selective glutamate receptor complex,presynaptic membrane,terminal bouton,perikaryon,postsynaptic membrane, |
| Protein Function | function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L-glutamate >> AMPA >> NMDA = 1S,3R-ACPD.,similarity:Belongs to the glutamate-gated ion channel (TC 1.A.10) family.,subunit:Associates with GRIK1 (both edited and unedited versions), GRIK2, or GRIK3 to form functional channels. Homomeric associations do not produce any channel activity., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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