ITN1771
ITN1771
- Catalog: ITN1771
- Gene/Protein: ITGB8
- Product Description: Immunotag™ ITB8 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | ITB8 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | ITB8 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | ITGB8 |
Accession No. | P26012 |
Description | integrin subunit beta 8(ITGB8) Homo sapiens This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Focal adhesion,ECM-receptor interaction,Cell adhesion molecules (CAMs),Regulates Actin and Cytoskeleton,Hypertrophic cardiomyopathy (HCM),Arrhythmogenic right ventricular cardiomyopathy (ARVC),Dilated cardiomyopathy, |
Protein Expression | Brain,Placenta,Uterus, |
Subcellular Localization | plasma membrane,integrin complex,cell surface,integrin alphav-beta8 complex,extracellular exosome, |
Protein Function | function:Integrin alpha-V/beta-8 is a receptor for fibronectin.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-8 associates with alpha-V.,tissue specificity:Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |