ITN1772
ITN1772
- Catalog: ITN1772
- Gene/Protein: ITGB1BP1 ICAP1
- Product Description: Immunotag™ ITBP1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ITBP1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | ITBP1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | ITGB1BP1 ICAP1 |
| Accession No. | O14713 O35671 |
| Description | integrin subunit beta 1 binding protein 1(ITGB1BP1) Homo sapiens The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016], |
| Protein Expression | Cervix carcinoma,Ovary, |
| Subcellular Localization | ruffle,nucleus,cytoplasm,cytosol,cytoskeleton,plasma membrane,focal adhesion,membrane,lamellipodium,perinuclear region of cytoplasm,extracellular exosome,cell periphery, |
| Protein Function | function:May play a role in the recruitment of beta-1 integrins to the focal contacts during integrin-dependent cell adhesion. Isoform 2 does not bind the integrin cytoplasmic domain-associated protein-1.,PTM:Isoform 1 appears to be phosphorylated. The degree of phosphorylation is regulated by integrin-dependent cell-matrix interaction.,similarity:Contains 1 PID domain.,subunit:Interacts specifically with the beta-1 integrin cytoplasmic domain-associated protein-1.,tissue specificity:Expressed in intestine, colon, testis, ovary, thymus, spleen and prostate., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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