ITN1798
ITN1798
- Catalog: ITN1798
- Gene/Protein: CDC14B
- Product Description: Immunotag™ CC14B Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CC14B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CC14B Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | CDC14B |
| Accession No. | O60729 Q6PFY9 |
| Description | cell division cycle 14B(CDC14B) Homo sapiens The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Cell_Cycle_G1S,Cell_Cycle_G2M_DNA, |
| Protein Expression | Placenta,Uterus, |
| Subcellular Localization | nucleus,nucleoplasm,nucleolus,cytoplasm,integral component of membrane,nuclear membrane, |
| Protein Function | catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,domain:Composed of two structurally equivalent A and B domains that adopt a dual specificity protein phosphatase (DSP) fold.,function:Dual-specificity phosphatase. Preferentially dephosphorylates proteins modified by proline-directed kinases.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.,subcellular location:Nucleolar during interphase., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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