ITN1838
ITN1838
- Catalog: ITN1838
- Gene/Protein: CYP4A22
- Product Description: Immunotag™ CP4AM Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CP4AM |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | CP4AM Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | CYP4A22 |
Accession No. | Q5TCH4 |
Description | cytochrome P450 family 4 subfamily A member 22(CYP4A22) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015], |
Cell Pathway/ Category | Fatty acid metabolism,Arachidonic acid metabolism,Retinol metabolism,PPAR,Vascular smooth muscle contraction, |
Protein Expression | Kidney,Liver, |
Subcellular Localization | endoplasmic reticulum membrane,integral component of membrane,organelle membrane, |
Protein Function | catalytic activity:Octane + reduced rubredoxin + O(2) = 1-octanol + oxidized rubredoxin + H(2)O.,caution:Was originally (PubMed:10860550) termed CYP4A11.,function:Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Shows no activity towards arachidonic acid and prostaglandin A1. Lacks functional activity in the kidney and does not contribute to renal 20-hydroxyeicosatetraenoic acid (20-HETE) biosynthesis.,online information:CYP4A22 alleles,similarity:Belongs to the cytochrome P450 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |