Datasheet |
|
Target Protein |
TAOK2 |
Clonality |
Polyclonal |
Storage/Stability |
-20°C/1 year |
Application |
WB,ELISA |
Recommended Dilution |
WB 1:500-2000 ELISA 1:5000-20000 |
Concentration |
1 mg/ml |
Reactive Species |
Human,Mouse,Rat |
Host Species |
Rabbit |
Immunogen |
Synthesized peptide derived from part region of human protein |
Specificity |
TAOK2 Polyclonal Antibody detects endogenous levels of protein. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form |
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name |
TAOK2 KIAA0881 MAP3K17 PSK PSK1 UNQ2971/PRO7431 |
Accession No. |
Q9UL54 Q6ZQ29 Q9JLS3 |
Description |
TAO kinase 2(TAOK2) Homo sapiens This gene encodes a serine/threonine protein kinase that is involved in many different processes, including, cell signaling, microtubule organization and stability, and apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011], |
Cell Pathway/ Category |
MAPK_ERK_Growth,MAPK_G_Protein, |
Protein Expression |
Brain,Clones donated by Kazusa DNA Research Inst.,Duodenum,Lung,Mammary carcinoma,Testis, |
Subcellular Localization |
nucleus,nucleolus,cytoplasm,cytoskeleton,integral component of membrane,cytoplasmic, membrane-bounded vesicle,dendrite,cytoplasmic vesicle membrane,cytoplasmic vesicle,receptor complex, |
Protein Function |
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Activates the JNK MAP kinase pathway through the specific activation of the upstream MKK3 and MKK6 kinases.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Found to be perinuclear and localized to vesicular compartment.,subunit:Interacts with MKK3 and MKK6 (By similarity). Self-associates.,tissue specificity:Ubiquitously expressed, with a higher level of expression in testis and brain., |
Usage |
For Research Use Only! Not for diagnostic or therapeutic procedures. |