ITN1925
ITN1925
- Catalog: ITN1925
- Gene/Protein: UVRAG
- Product Description: Immunotag™ UVRAG Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | UVRAG |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | UVRAG Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | UVRAG |
| Accession No. | Q9P2Y5 |
| Description | UV radiation resistance associated(UVRAG) Homo sapiens This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008], |
| Protein Expression | Heart,Liver,Peripheral Nervous System, |
| Subcellular Localization | chromosome, centromeric region,cytoplasm,lysosome,early endosome,late endosome,endoplasmic reticulum,centrosome,midbody,HOPS complex,protein complex,phagocytic vesicle,DNA-dependent protein kinase complex, |
| Protein Function | disease:Disrupted by a Inv(11)(q13.5;q25) inversion in a patient with heterotaxy (left-right axis malformation).,similarity:Contains 1 C2 domain.,tissue specificity:Highly expressed in brain, lung, kidney and liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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