ITN1998
ITN1998
- Catalog: ITN1998
- Gene/Protein: MDGA1 MAMDC3
- Product Description: Immunotag™ MDGA1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | MDGA1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | MDGA1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | MDGA1 MAMDC3 |
| Accession No. | Q8NFP4 Q0PMG2 P85171 |
| Description | MAM domain containing glycosylphosphatidylinositol anchor 1(MDGA1) Homo sapiens This gene encodes a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that is expressed predominantly in the developing nervous system. In addition to possessing several cell adhesion molecule-like domains, the mature protein has six Ig-like domains, a single fibronectin type III domain, a MAM domain and a C-terminal GPI-anchoring site. Studies in other mammals suggest this protein plays a role in cell adhesion, migration, and axon guidance and, in the developing brain, neuronal migration. In humans, this gene is associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2016], |
| Protein Expression | Cerebellum,Plasma, |
| Subcellular Localization | extracellular space,Golgi apparatus,plasma membrane,membrane,anchored component of plasma membrane, |
| Protein Function | function:Required for radial migration of cortical neurons in the superficial layer of the neocortex.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 1 MAM domain.,similarity:Contains 6 Ig-like (immunoglobulin-like) domains.,subcellular location:Associated with lipid rafts.,subunit:Interacts heterophilically through its MAM domain with proteins in axon-rich regions and through its Ig-like domains with proteins in differentiating muscle.,tissue specificity:Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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