ITN2019
ITN2019
- Catalog: ITN2019
- Gene/Protein: TXNDC5 TLP46 UNQ364/PRO700
- Product Description: Immunotag™ TXND5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TXND5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TXND5 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | TXNDC5 TLP46 UNQ364/PRO700 |
| Accession No. | Q8NBS9 Q91W90 |
| Description | thioredoxin domain containing 5(TXNDC5) Homo sapiens This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene. [provided by RefSeq, Dec 2010], |
| Protein Expression | Eye,Liver,Lymph,Lymph node,Ovary,PCR rescued clones,Retina,Spleen,Stomach, |
| Subcellular Localization | cell,endoplasmic reticulum,endoplasmic reticulum lumen,lysosomal lumen,extracellular exosome, |
| Protein Function | function:Involved in the development of lysosome-related organelles, such as melanosomes and platelet-dense granules.,function:Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast.,similarity:Belongs to the Muted family.,similarity:Belongs to the protein disulfide isomerase family.,similarity:Contains 2 thioredoxin domains.,similarity:Contains 3 thioredoxin domains.,subunit:Interacts with pallidin. Interacts with dystrobrevin binding protein 1 and CNO/cappuccino (By similarity). Part of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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