ITN2029
ITN2029
- Catalog: ITN2029
- Gene/Protein: LPPR4 KIAA0455 PRG1
- Product Description: Immunotag™ LPPR4 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | LPPR4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | LPPR4 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | LPPR4 KIAA0455 PRG1 |
Accession No. | Q7Z2D5 Q7TME0 Q7TMB7 |
Description | phospholipid phosphatase related 4(PLPPR4) Homo sapiens The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009], |
Protein Expression | Amygdala,Brain, |
Subcellular Localization | plasma membrane,integral component of plasma membrane, |
Protein Function | catalytic activity:A 3-sn-phosphatidate + H(2)O = a 1,2-diacyl-sn-glycerol + phosphate.,function:Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus.,similarity:Belongs to the PA-phosphatase related phosphoesterase family.,tissue specificity:Specifically expressed in neurons., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |