ITN2073
ITN2073
- Catalog: ITN2073
- Gene/Protein: FHL2 DRAL SLIM3
- Product Description: Immunotag™ FHL2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FHL2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | FHL2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | FHL2 DRAL SLIM3 |
| Accession No. | Q14192 O70433 O35115 |
| Description | four and a half LIM domains 2(FHL2) Homo sapiens This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2016], |
| Protein Expression | Bone marrow,Heart,Heart muscle,Leukocyte,Ovary,Placenta,Skeletal muscle,Whi |
| Subcellular Localization | nucleus,nucleoplasm,focal adhesion,actin cytoskeleton,Z disc,M band, |
| Protein Function | domain:The third LIM zinc-binding mediates interaction with E4F1.,function:May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 3 LIM zinc-binding domains.,similarity:Contains 4 LIM zinc-binding domains.,subunit:Interacts with ZNF638 and TTN/titin. Interacts with E4F1.,tissue specificity:Expressed in skeletal muscle and heart., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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