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ITN2178

ITN2178
  • Gene/Protein: NR5A2 B1F CPF FTF
  • Product Description: Immunotag™ NR5A2 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ NR5A2 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein NR5A2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity NR5A2 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name NR5A2 B1F CPF FTF
Accession No. O00482 P45448 Q9QWM1
Description nuclear receptor subfamily 5 group A member 2(NR5A2) Homo sapiens The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development. [provided by RefSeq, Jun 2016],
Cell Pathway/ Category Maturity onset diabetes of the young,
Protein Expression Hepatocellular carcinoma,Hepatoma,Liver,
Subcellular Localization nucleus,nucleoplasm,cytoplasm,RNA polymerase II transcription factor complex,
Protein Function function:Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR5 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Binds DNA as a monomer (By similarity). Interacts with GRIP1, NCOA2 and NR0B2.,tissue specificity:Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in hepG2. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and hepG2 cells.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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