ITN2186
ITN2186
- Catalog: ITN2186
- Gene/Protein: CLEC1B CLEC2 UNQ721/PRO1384
- Product Description: Immunotag™ CLC1B Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CLC1B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CLC1B Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | CLEC1B CLEC2 UNQ721/PRO1384 |
| Accession No. | Q9P126 Q9JL99 |
| Description | C-type lectin domain family 1 member B(CLEC1B) Homo sapiens Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011], |
| Protein Expression | Liver,Testis, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane, |
| Protein Function | function:Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.,online information:CLEC-2,PTM:Glycosylated.,PTM:Phosphorylated on tyrosine residue in response to rhodocytin binding.,similarity:Contains 1 C-type lectin domain.,subunit:Monomer.,tissue specificity:Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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