ITN2234
ITN2234
- Catalog: ITN2234
- Gene/Protein: LUM LDC SLRR2D
- Product Description: Immunotag™ LUM Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | LUM |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 30-110 |
| Specificity | LUM Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | LUM LDC SLRR2D |
| Accession No. | P51884 P51885 P51886 |
| Description | lumican(LUM) Homo sapiens This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008], |
| Protein Expression | Cartilage,Cornea,Human lung,Intestine,Liver,Lung,Placenta,Plasma,Prostate, |
| Subcellular Localization | extracellular region,proteinaceous extracellular matrix,fibrillar collagen trimer,extracellular space,Golgi lumen,extracellular matrix,lysosomal lumen,extracellular exosome, |
| Protein Function | developmental stage:Present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan.,PTM:Sulfated on tyrosine residue(s).,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class II subfamily.,similarity:Contains 12 LRR (leucine-rich) repeats.,subunit:Binds to laminin.,tissue specificity:Cornea and other tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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