Datasheet |
|
Target Protein |
ITLN1 |
Clonality |
Polyclonal |
Storage/Stability |
-20°C/1 year |
Application |
WB,ELISA |
Recommended Dilution |
WB 1:500-2000 ELISA 1:5000-20000 |
Concentration |
1 mg/ml |
Reactive Species |
Human |
Host Species |
Rabbit |
Immunogen |
Synthesized peptide derived from human protein . at AA range: 110-190 |
Specificity |
ITLN1 Polyclonal Antibody detects endogenous levels of protein. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form |
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name |
ITLN1 INTL ITLN LFR UNQ640/PRO1270 |
Accession No. |
Q8WWA0 |
Description |
developmental stage:Found in fetal small intestine and thymus.,function:Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.,mass spectrometry: PubMed:17621593,PTM:N-glycosylated.,similarity:Contains 1 fibrinogen C-terminal domain.,subcellular location:Enriched in lipid rafts.,subunit:Homotrimer; disulfide-linked.,tissue specificity:Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus., |
Protein Expression |
Adipose tissue,Lung,Ovary,Placenta,Small intestine, |
Subcellular Localization |
anchored component of membrane,brush border membrane,receptor complex,membrane raft,extracellular exosome, |
Protein Function |
developmental stage:Found in fetal small intestine and thymus.,function:Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.,mass spectrometry: PubMed:17621593,PTM:N-glycosylated.,similarity:Contains 1 fibrinogen C-terminal domain.,subcellular location:Enriched in lipid rafts.,subunit:Homotrimer; disulfide-linked.,tissue specificity:Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus., |
Usage |
For Research Use Only! Not for diagnostic or therapeutic procedures. |