ITN2243
ITN2243
- Catalog: ITN2243
- Gene/Protein: HPN TMPRSS1
- Product Description: Immunotag™ HEPS Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | HEPS |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 350-430 |
| Specificity | HEPS Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | HPN TMPRSS1 |
| Accession No. | P05981 O35453 Q05511 |
| Description | hepsin(HPN) Homo sapiens This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013], |
| Protein Expression | Liver,Mammary gland,Pancreas,Spleen, |
| Subcellular Localization | endoplasmic reticulum membrane,plasma membrane,integral component of plasma membrane,cell-cell junction,cell surface,membrane,integral component of membrane,apical plasma membrane,nuclear membrane,neuronal cell body,extracellular exosome, |
| Protein Function | catalytic activity:Cleavage after basic amino-acid residues, with Arg strongly preferred to Lys.,function:Plays an essential role in cell growth and maintenance of cell morphology.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 SRCR domain.,tissue specificity:Present in most tissues, with the highest level in liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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