ITN2367
ITN2367
- Catalog: ITN2367
- Gene/Protein: FKBP2 FKBP13
- Product Description: Immunotag™ FKBP2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FKBP2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 80-160 |
| Specificity | FKBP2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | FKBP2 FKBP13 |
| Accession No. | P26885 P45878 |
| Description | FK506 binding protein 2(FKBP2) Homo sapiens The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008], |
| Protein Expression | Colon carcinoma,Placenta, |
| Subcellular Localization | endoplasmic reticulum,endoplasmic reticulum membrane,extracellular exosome, |
| Protein Function | catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by both FK506 and rapamycin.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the FKBP-type PPIase family.,similarity:Belongs to the FKBP-type PPIase family. FKBP2 subfamily.,similarity:Contains 1 PPIase FKBP-type domain.,subunit:Interacts with ARFGEF1/BIG1 and the C-terminal of EPB41L2.,tissue specificity:T-cells and thymus., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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