ITN2393
ITN2393
- Catalog: ITN2393
- Gene/Protein: SCARF1 KIAA0149 SREC
- Product Description: Immunotag™ SREC Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | SREC |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 390-470 |
Specificity | SREC Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | SCARF1 KIAA0149 SREC |
Accession No. | Q14162 Q5ND28 |
Description | scavenger receptor class F member 1(SCARF1) Homo sapiens The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013], |
Protein Expression | Bone marrow,Platelet,Testis,Umbilical vein endothelial cell, |
Subcellular Localization | plasma membrane,integral component of membrane,endocytic vesicle membrane, |
Protein Function | caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein.,similarity:Contains 6 EGF-like domains.,subunit:Heterophilic interaction with SREC2 via its extracellular domain. The heterophilic interaction is suppressed by the presence of ligand such as Ac-LDL.,tissue specificity:Endothelial cells., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |