ITN2395
ITN2395
- Catalog: ITN2395
- Gene/Protein: TIPARP PARP7
- Product Description: Immunotag™ PARPT Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PARPT |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 450-530 |
Specificity | PARPT Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | TIPARP PARP7 |
Accession No. | Q7Z3E1 Q8C1B2 |
Description | TCDD inducible poly(ADP-ribose) polymerase(TIPARP) Homo sapiens This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010], |
Protein Expression | Brain,Endometrial tumor,Testis, |
Subcellular Localization | nucleus, |
Protein Function | catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,function:Poly [ADP-ribose] polymerase using NAD(+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.,similarity:Contains 1 C3H1-type zinc finger.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 1 WWE domain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |