ITN2452
ITN2452
- Catalog: ITN2452
- Gene/Protein: ID3 1R21 BHLHB25 HEIR1
- Product Description: Immunotag™ ID3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ID3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 68-117 |
| Specificity | ID3 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | ID3 1R21 BHLHB25 HEIR1 |
| Accession No. | Q02535 P41133 P41138 |
| Description | inhibitor of DNA binding 3, HLH protein(ID3) Homo sapiens The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. [provided by RefSeq, Aug 2011], |
| Cell Pathway/ Category | TGF-beta, |
| Protein Expression | Blood,Skin, |
| Subcellular Localization | nucleus,nucleoplasm,cytoplasm,microtubule cytoskeleton, |
| Protein Function | function:ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.,induction:By phorbol 12-myristate 13-acetate (PMA).,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with COPS5 and COPS7A (By similarity). Homodimer, and heterodimer with other HLH proteins.,tissue specificity:Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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