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ITN2525

  • Gene/Protein: GPER CEPR CMKRL2 DRY12 GPR30
  • Product Description: Immunotag™ GPER Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

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ITN2525

Immunotag™ GPER Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein GPER
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 300-380
Specificity GPER Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name GPER CEPR CMKRL2 DRY12 GPR30
Accession No. Q99527 Q8BMP4 O08878
Description G protein-coupled estrogen receptor 1(GPER1) Homo sapiens This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008],
Protein Expression Brain,Liver,Uterus,
Subcellular Localization Golgi membrane,intracellular,nucleus,nuclear envelope,cytoplasm,early endosome,endoplasmic reticulum,endoplasmic reticulum membrane,Golgi apparatus,trans-Golgi network,plasma membrane,integral component of plasma
Protein Function function:Receptor for estrogen.,similarity:Belongs to the G-protein coupled receptor 1 family.,subcellular location:Protein has been detected in the cell membrane, endoplasmic reticulum and Golgi apparatus. It is currently unclear whether this is a cell surface or intracellular receptor.,tissue specificity:Ubiquitously expressed, but is most abundant in placenta. In brain regions, expressed as a 2.8 kb transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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