ITN2525
ITN2525
- Catalog: ITN2525
- Gene/Protein: GPER CEPR CMKRL2 DRY12 GPR30
- Product Description: Immunotag™ GPER Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GPER |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 300-380 |
| Specificity | GPER Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | GPER CEPR CMKRL2 DRY12 GPR30 |
| Accession No. | Q99527 Q8BMP4 O08878 |
| Description | G protein-coupled estrogen receptor 1(GPER1) Homo sapiens This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Liver,Uterus, |
| Subcellular Localization | Golgi membrane,intracellular,nucleus,nuclear envelope,cytoplasm,early endosome,endoplasmic reticulum,endoplasmic reticulum membrane,Golgi apparatus,trans-Golgi network,plasma membrane,integral component of plasma |
| Protein Function | function:Receptor for estrogen.,similarity:Belongs to the G-protein coupled receptor 1 family.,subcellular location:Protein has been detected in the cell membrane, endoplasmic reticulum and Golgi apparatus. It is currently unclear whether this is a cell surface or intracellular receptor.,tissue specificity:Ubiquitously expressed, but is most abundant in placenta. In brain regions, expressed as a 2.8 kb transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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