ITN2552
ITN2552
- Catalog: ITN2552
- Gene/Protein: GPR33
- Product Description: Immunotag™ GPR33 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GPR33 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | GPR33 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | GPR33 |
| Accession No. | Q49SQ1 O88416 |
| Description | G protein-coupled receptor 33 (gene/pseudogene)(GPR33) Homo sapiens This gene has been identified as an orphan chemoattractant G-protein-coupled receptors (GPCR) pseudogene. Studies have shown that the inactivated gene is present as the predominant allele in the human population. A small fraction of the human population has been found to harbor an intact allele.[provided by RefSeq, Oct 2010], |
| Subcellular Localization | integral component of plasma membrane,integral component of membrane, |
| Protein Function | function:Orphan receptor; could be a chemoattractant receptor.,polymorphism:In most individuals a nonsense mutation transforms the Arg-140 into a premature stop codon. Out of 1217 individuals, 1166 had a stop codon in both alleles, 50 were heterozygous and only one (in the Philippines) had Arg-140 in both alleles. GPR33 has undergone independent pseudogenization in human, chimpanzee, orangutan, siamang and rat. This selective inactivation may be due to its interaction with a putative pathogen that could use GPR33 as a receptor for cell invasion.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in spleen, lung, heart, liver, kidney, pancreas, thymus, gonads and leukocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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