ITN2585
ITN2585
- Catalog: ITN2585
- Gene/Protein: OPRL1 OOR ORL1
- Product Description: Immunotag™ OPRX Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | OPRX |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | OPRX Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | OPRL1 OOR ORL1 |
| Accession No. | P41146 P35377 P35370 |
| Description | opioid related nociceptin receptor 1(OPRL1) Homo sapiens The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an ad |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Brain,Brain stem,Lymphocyte, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane,cytoplasmic, membrane-bounded vesicle,cytoplasmic vesicle,neuron projection, |
| Protein Function | function:Receptor for the neuropeptide nociceptin/orphanin FQ. Has a potential role in modulating a number of brain functions, including instinctive behaviors and emotions. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.,induction:By phytohemagglutinin (PHA).,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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