ITN2839
ITN2839
- Catalog: ITN2839
- Gene/Protein: PKP3
- Product Description: Immunotag™ PKP3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | PKP3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | PKP3 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PKP3 |
| Accession No. | Q9Y446 Q9QY23 |
| Description | plakophilin 3(PKP3) Homo sapiens This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014], |
| Protein Expression | Colon,Colon carcinoma,Epithelium,Placenta, |
| Subcellular Localization | nucleus,plasma membrane,cell-cell junction,cell-cell adherens junction,desmosome, |
| Protein Function | function:May play a role in junctional plaques.,similarity:Belongs to the beta-catenin family.,similarity:Contains 8 ARM repeats.,subcellular location:Nuclear and associated with desmosomes.,tissue specificity:Found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines. Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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