ITN2844
ITN2844
- Catalog: ITN2844
- Gene/Protein: PFN2
- Product Description: Immunotag™ PROF2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | PROF2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | PROF2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PFN2 |
| Accession No. | P35080 Q9JJV2 Q9EPC6 |
| Description | profilin 2(PFN2) Homo sapiens The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Regulates Actin and Cytoskeleton, |
| Protein Expression | Brain,Epithelium,Fetal brain cortex,Lung,Uterus, |
| Subcellular Localization | cytoplasm,cytoskeleton,integral component of membrane,terminal bouton,extracellular exosome, |
| Protein Function | function:Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.,similarity:Belongs to the profilin family.,subunit:Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.,tissue specificity:Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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