ITN2865
ITN2865
- Catalog: ITN2865
- Gene/Protein: OCLN
- Product Description: Immunotag™ OCLN Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | OCLN |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | OCLN Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | OCLN |
| Accession No. | Q16625 Q61146 Q6P6T5 |
| Description | occludin(OCLN) Homo sapiens This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011], |
| Cell Pathway/ Category | Cell adhesion molecules (CAMs),Tight junction,Leukocyte transendothelial migration,Pathogenic Escherichia coli infection, |
| Subcellular Localization | plasma membrane,cell-cell junction,bicellular tight junction,integral component of membrane,apical plasma membrane,apicolateral plasma membrane,cell junction,endocytic vesicle,cytoplasmic vesicle, |
| Protein Function | protein complex assembly, cellular amino acid derivative metabolic process, sulfur metabolic process, nucleoside metabolic process, ribonucleoside metabolic process, purine nucleoside metabolic process, macromolecular complex subunit organization, purine ribonucleoside metabolic process, S-adenosylhomocysteine metabolic process, S-adenosylmethionine metabolic process, macromolecular complex assembly, protein complex biogenesis, |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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