ITN2919
ITN2919
- Catalog: ITN2919
- Gene/Protein: SRD5A1
- Product Description: Immunotag™ S5A1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | S5A1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | S5A1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SRD5A1 |
| Accession No. | P18405 Q68FF9 P24008 |
| Description | steroid 5 alpha-reductase 1(SRD5A1) Homo sapiens Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008], |
| Cell Pathway/ Category | Steroid hormone biosynthesis,Androgen and estrogen metabolism, |
| Protein Expression | Adrenal gland,Brain,Eye,Urinary bladder, |
| Subcellular Localization | endoplasmic reticulum membrane,integral component of membrane,organelle membrane,neuronal cell body,myelin sheath,perinuclear region of cytoplasm,cell body fiber, |
| Protein Function | catalytic activity:A 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-Delta(4)-steroid + reduced acceptor.,function:Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.,induction:Its expression is regulated by androgens such as testosterone.,online information:5-alpha reductase entry,similarity:Belongs to the steroid 5-alpha reductase family.,tissue specificity:Liver and prostate (at a low level)., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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