ITN2922
ITN2922
- Catalog: ITN2922
- Gene/Protein: TGM3
- Product Description: Immunotag™ TGM3 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | TGM3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | TGM3 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | TGM3 |
Accession No. | Q08188 Q08189 D4A5U3 |
Description | transglutaminase 3(TGM3) Homo sapiens Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq, Jul 2008], |
Protein Expression | Foreskin,Osteosarcoma,Tongue, |
Subcellular Localization | cytoplasm,extrinsic component of cytoplasmic side of plasma membrane,extracellular exosome, |
Protein Function | catalytic activity:Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).,cofactor:Binds 1 calcium ion per subunit.,function:Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It is responsible for the later stages of cell envelope formation in the epidermis and the hair follicle.,PTM:Activated by proteolytic processing.,similarity:Belongs to the transglutaminase superfamily. Transglutaminase family.,subunit:This enzyme consists of two polypeptide chains, which are synthesized as a precursor form of a single polypeptide., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |