ITN2925
ITN2925
- Catalog: ITN2925
- Gene/Protein: SEPT4 ARTS PNUTL2 SEP4 hucep-7
- Product Description: Immunotag™ SEPT4 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | SEPT4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SEPT4 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | SEPT4 ARTS PNUTL2 SEP4 hucep-7 |
| Accession No. | O43236 P28661 |
| Description | septin 4(SEPT4) Homo sapiens This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. [provided by RefSeq, Nov 2010], |
| Protein Expression | Brain,Fetal brain,Hippocampus,Liver, |
| Subcellular Localization | nucleus,nucleoplasm,mitochondrion,cytoskeleton,myelin sheath,sperm annulus, |
| Protein Function | function:Involved in cytokinesis .,similarity:Belongs to the septin family.,subcellular location:Only observed in tumor tissue cells.,subunit:May assemble into a multicomponent structure.,tissue specificity:Expressed ubiquitously in adult and fetal tissues with particularly high expression in adult heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancer and malignant melanoma samples., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|