ITN2936
ITN2936
- Catalog: ITN2936
- Gene/Protein: GNAI1
- Product Description: Immunotag™ GNAI1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | GNAI1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | GNAI1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | GNAI1 |
Accession No. | P63096 B2RSH2 P10824 |
Description | G protein subunit alpha i1(GNAI1) Homo sapiens Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012], |
Cell Pathway/ Category | Chemokine,Axon guidance,Tight junction,Gap junction,Leukocyte transendothelial migration,Long-term depression,Progesterone-mediated oocyte maturation,Melanogenesis, |
Protein Expression | Adipocyte,Brain, |
Subcellular Localization | nucleus,cytoplasm,lysosomal membrane,centrosome,heterotrimeric G-protein complex,plasma membrane,midbody,membrane raft,extracellular exosome, |
Protein Function | function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |