ITN2937
ITN2937
- Catalog: ITN2937
- Gene/Protein: MUC3A MUC3
- Product Description: Immunotag™ MUC3A Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | MUC3A |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p |
Recommended Dilution | IHC-p 1:50-300 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | MUC3A Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | MUC3A MUC3 |
Accession No. | Q02505 |
Description | mucin 3A, cell surface associated(MUC3A) Homo sapiens The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 [PubMed 7778880]).[supplied by OMIM, Aug 2008], |
Protein Expression | Colon mucosa,Intestinal,Intestine,Small intestine, |
Subcellular Localization | extracellular region,extracellular space,Golgi lumen,integral component of membrane,apical plasma membrane, |
Protein Function | Additional isoforms seem to exist,function:Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.,function:Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling.,PTM:Highly O-glycosylated and probably also N-glycosylated.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 SEA domain.,tissue specificity:Broad specificity; small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas and gall bladder.,tissue specificity:Fetal and adult small intestine and fetal and adult colon., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |