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ITN2990

ITN2990
  • Catalog: ITN2990
  • Gene/Protein: RPA4
  • Product Description: Immunotag™ RFA4 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ RFA4 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein RFA4
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity RFA4 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name RPA4
Accession No. Q13156
Description replication protein A4(RPA4) Homo sapiens This gene encodes a single-stranded DNA-binding protein that is the 30-kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.[provided by RefSeq, Apr 2010],
Cell Pathway/ Category DNA replication,Nucleotide excision repair,Mismatch repair,Homologous recombination,
Subcellular Localization nucleus,nucleoplasm,DNA replication factor A complex,
Protein Function function:Absolutely required for simian virus 40 DNA replication in vitro. It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein.,subunit:Interacts with RPA1 and RPA3. In a tissue-specic manner, may replace RPA2 in the replication protein A heterotrimer.,tissue specificity:Preferentially expressed in placental and colon mucosa.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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