ITN3002
ITN3002
- Catalog: ITN3002
- Gene/Protein: VPS11 RNF108 PP3476
- Product Description: Immunotag™ VPS11 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | VPS11 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | VPS11 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | VPS11 RNF108 PP3476 |
| Accession No. | Q9H270 Q91W86 |
| Description | VPS11, CORVET/HOPS core subunit(VPS11) Homo sapiens Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014], |
| Protein Expression | Brain,Eye,Human lung,Skin, |
| Subcellular Localization | intracellular,lysosome,lysosomal membrane,endosome,early endosome,late endosome,autophagosome,actin filament,AP-3 adaptor complex,clathrin-coated vesicle,endocytic vesicle,HOPS complex,late endosome membrane,G |
| Protein Function | function:May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.,similarity:Belongs to the VPS11 family.,similarity:Contains 1 clathrin repeat.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.,subunit:Large hetero-oligomeric complex together with VPS16, VPS18 and VPS33A. Interacts with STX7.,tissue specificity:Ubiquitous. Expression was highest in heart and low in lung., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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