ITP0732
ITP0732
- Catalog: ITP0732
- Gene/Protein: CSNK2B
- Product Description: Immunotag™ Casein Kinase IIβ (phospho Ser209) Polyclonal Antibody
490.0000
Price in reward points: 490
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CK Kinase IIβ (Ser209) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Casein Kinase IIβ (phospho Ser209) |
| Specificity | Phospho-Casein Kinase IIβ (S209) Polyclonal Antibody detects endogenous levels of Casein Kinase IIβ protein only when phosphorylated at S209. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CSNK2B |
| Accession No. | P67870 P67871 P67874 |
| Alternate Names | CSNK2B; CK2N; G5A; Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a |
| Description | casein kinase 2 beta(CSNK2B) Homo sapiens This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013], |
| Cell Pathway/ Category | WNT,WNT-T CELLAdherens_Junction,Adherens_Junction, |
| Protein Expression | Brain,Epithelium, |
| Subcellular Localization | nucleus,nucleoplasm,cytoplasm,cytosol,plasma membrane,protein kinase CK2 complex,PcG protein complex,extracellular exosome, |
| Protein Function | function:Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.,PTM:N-glycosylated.,PTM:Phosphorylated by alpha subunit.,similarity:Belongs to the casein kinase 2 subunit beta family.,similarity:Contains 1 UPAR/Ly6 domain.,subunit:Forms oligomer.,subunit:Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. Interacts with TCTEX1D3 (By similarity). Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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