ITP1019
ITP1019
- Catalog: ITP1019
- Gene/Protein: NR4A1
- Product Description: Immunotag™ Nur77 (phospho Ser351) Polyclonal Antibody
490.0000
Price in reward points: 490
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Nur77 (Ser351) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Nur77 (phospho Ser351) |
| Specificity | Phospho-Nur77 (S351) Polyclonal Antibody detects endogenous levels of Nur77 protein only when phosphorylated at S351. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | NR4A1 |
| Accession No. | P22736 P12813 P22829 |
| Alternate Names | NR4A1; GFRP1; HMR; NAK1; Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3 |
| Description | nuclear receptor subfamily 4 group A member 1(NR4A1) Homo sapiens This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein, |
| Protein Expression | Colon adenocarcinoma,Fetal skeletal muscle,Skeletal muscle, |
| Subcellular Localization | nucleus,nucleoplasm,transcription factor complex,cytoplasm,nuclear membrane, |
| Protein Function | function:Orphan nuclear receptor.,induction:By growth-stimulating agents.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR4 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with GADD45GIP1.,tissue specificity:Fetal muscle and adult liver, brain and thyroid., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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