Datasheet |
|
Target Protein |
Syndecan-4 (Ser179) |
Clonality |
Polyclonal |
Storage/Stability |
-20°C/1 year |
Application |
IHC-p,IF,ELISA |
Recommended Dilution |
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration |
1 mg/ml |
Reactive Species |
Human,Mouse,Rat |
Host Species |
Rabbit |
Immunogen |
Synthesized phospho-peptide around the phosphorylation site of human Syndecan-4 (phospho Ser179) |
Specificity |
Phospho-Syndecan-4 (S179) Polyclonal Antibody detects endogenous levels of Syndecan-4 protein only when phosphorylated at S179. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name |
SDC4 |
Accession No. |
P31431 O35988 P34901 |
Alternate Names |
SDC4; Syndecan-4; SYND4; Amphiglycan; Ryudocan core protein |
Description |
syndecan 4(SDC4) Homo sapiens The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category |
ECM-receptor interaction,Cell adhesion molecules (CAMs), |
Protein Expression |
Lung,Lung fibroblast,Placenta,Stomach,Thalamus, |
Subcellular Localization |
Golgi lumen,plasma membrane,integral component of plasma membrane,focal adhesion,cell surface,integral component of membrane,costamere,lysosomal lumen,membrane raft,extracellular exosome, |
Protein Function |
function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Homodimer. Interacts with CDCP1, with GIPC PDZ domain and with NUDT16L1/SDOS (By similarity). Interacts with SDCBP.,tissue specificity:Expressed in epithelial and fibroblastic cells., |
Usage |
For Research Use Only! Not for diagnostic or therapeutic procedures. |