ITP1179
ITP1179
- Catalog: ITP1179
- Gene/Protein: GATA3
- Product Description: Immunotag™ GATA-3 (phospho Ser308) Polyclonal Antibody
490.0000
Price in reward points: 490
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GATA-3 (Ser308) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IF,ELISA |
| Recommended Dilution | Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GATA3 around the phosphorylation site of Ser308. AA range:274-323 |
| Specificity | Phospho-GATA-3 (S308) Polyclonal Antibody detects endogenous levels of GATA-3 protein only when phosphorylated at S308. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GATA3 |
| Accession No. | P23771 P23772 |
| Alternate Names | GATA3; Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3 |
| Description | GATA binding protein 3(GATA3) Homo sapiens This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009], |
| Protein Expression | Cervix,Placenta,T-cell, |
| Subcellular Localization | nuclear chromatin,nucleus,nucleoplasm,transcription factor complex,nucleolus, |
| Protein Function | disease:Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.,function:Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:T-cells and endothelial cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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