ITT0031
ITT0031
- Catalog: ITT0031
- Gene/Protein: ADCY9
- Product Description: Immunotag™ A Cyclase IX Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | A Cyclase IX |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ADCY9. AA range:137-186 |
| Specificity | A Cyclase IX Polyclonal Antibody detects endogenous levels of A Cyclase IX protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ADCY9 |
| Accession No. | O60503 P51830 |
| Alternate Names | ADCY9; KIAA0520; Adenylate cyclase type 9; ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9 |
| Description | adenylate cyclase 9(ADCY9) Homo sapiens Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Purine metabolism,Calcium,Chemokine,Oocyte meiosis,Vascular smooth muscle contraction,Gap junction,GnRH,Progesterone-mediated oocyte maturation,Melanogenesis,Vibrio cholerae infection,Dilated cardiomyopathy, |
| Protein Expression | Brain,Epithelium,Heart, |
| Subcellular Localization | intracellular,plasma membrane,integral component of plasma membrane,integral component of membrane,axon,dendrite, |
| Protein Function | catalytic activity:ATP = 3',5'-cyclic AMP + diphosphate.,cofactor:Binds 2 magnesium ions per subunit.,enzyme regulation:Insensitive to calcium/calmodulin, forskolin and somatostatin. Stimulated by beta-adrenergic receptor activation.,function:May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 2 guanylate cyclase domains.,tissue specificity:Expressed in multiple cells of the lung, with expression highest in airway smooth muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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