ITT0034
ITT0034
- Catalog: ITT0034
- Gene/Protein: ADCY7
- Product Description: Immunotag™ A Cyclase VII Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | A Cyclase VII |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,IF,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human ADCY7. AA range:191-240 |
Specificity | A Cyclase VII Polyclonal Antibody detects endogenous levels of A Cyclase VII protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ADCY7 |
Accession No. | P51828 P51829 |
Alternate Names | ADCY7; KIAA0037; Adenylate cyclase type 7; ATP pyrophosphate-lyase 7; Adenylate cyclase type VII; Adenylyl cyclase 7 |
Description | adenylate cyclase 7(ADCY7) Homo sapiens This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013], |
Cell Pathway/ Category | Purine metabolism,Calcium,Chemokine,Oocyte meiosis,Vascular smooth muscle contraction,Gap junction,GnRH,Progesterone-mediated oocyte maturation,Melanogenesis,Dilated cardiomyopathy, |
Protein Expression | Blood,Bone marrow, |
Subcellular Localization | intracellular,plasma membrane,integral component of membrane, |
Protein Function | catalytic activity:ATP = 3',5'-cyclic AMP + diphosphate.,cofactor:Binds 2 magnesium ions per subunit.,function:This is a membrane-bound, calcium-inhibitable adenylyl cyclase.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 2 guanylate cyclase domains., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |