ITT0128
ITT0128
- Catalog: ITT0128
- Gene/Protein: ADORA1
- Product Description: Immunotag™ Adenosine A1-R Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Adenosine A1-R |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Adenosine A1-R, at AA range: 250-330 |
| Specificity | Adenosine A1-R Polyclonal Antibody detects endogenous levels of Adenosine A1-R protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ADORA1 |
| Accession No. | P30542 Q60612 P25099 |
| Alternate Names | ADORA1; Adenosine receptor A1 |
| Description | adenosine A1 receptor(ADORA1) Homo sapiens The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Brain,Heart,Hippocampus, |
| Subcellular Localization | endoplasmic reticulum,plasma membrane,integral component of plasma membrane,postsynaptic density,integral component of membrane,basolateral plasma membrane,axolemma,asymmetric synapse,presynaptic membrane,neuronal cell body,terminal bouton |
| Protein Function | function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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